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Quantum mechanical/molecular mechanical and docking study of the novel analogues based on hybridization of common pharmacophores as potential anti-breast cancer agents

In an attempt to identify some new potential leads as anti-breast cancer agents, novel hybrid compounds were designed by molecular hybridization approach. These derivatives were structurally derived from hybrid benzofuran–imidazole and quinazolinone derivatives, which had shown good cytotoxicity aga...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Asadi, Parvin, Khodarahmi, Ghadamali, Farrokhpour, Hossein, Hassanzadeh, Farshid, Saghaei, Lotfollah
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465832/
https://ncbi.nlm.nih.gov/pubmed/28626481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.207204
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