Plasminogen-activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells.

We have analyzed the role of plasminogen-activator inhibitor type 1 (PAI-1) in the regulation of tumor cell-mediated extracellular matrix degradation. Immunocytochemical analysis revealed PAI-1 associated with microgranular and fibrillar material of the extracellular matrix and demonstrated the pres...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Cajot, J F, Bamat, J, Bergonzelli, G E, Kruithof, E K, Medcalf, R L, Testuz, J, Sordat, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54657/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2169614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.6939
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