Hepatitis C Virus Core Protein Induces an Anergic State Characterized by Decreased Interleukin-2 Production and Perturbation of Mitogen-Activated Protein Kinase Responses

Alterations of cytokine responses are thought to favor the establishment of persistent hepatitis C virus (HCV) infections, enhancing the risk of liver cirrhosis and hepatocellular carcinoma. Here we demonstrate that the expression of the HCV core (C) protein in stably transfected T cells correlates...

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Detalhes bibliográficos
Main Authors: Sundström, Sara, Ota, Seisuke, Dimberg, Lina Y., Masucci, Maria G., Bergqvist, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546561/
https://ncbi.nlm.nih.gov/pubmed/15681425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2230-2239.2005
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