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Roles of the ITAM and PY Motifs of Epstein-Barr Virus Latent Membrane Protein 2A in the Inhibition of Epithelial Cell Differentiation and Activation of β-Catenin Signaling

Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A) is important for maintenance of latency in infected B lymphocytes. Through its immunoreceptor tyrosine-based activation motif (ITAM) and PY motifs, LMP2A is able to block B-cell receptor (BCR) signaling, bind BCR-associated kinases, and man...

詳細記述

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書誌詳細
主要な著者: Morrison, Jennifer A., Raab-Traub, Nancy
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC546559/
https://ncbi.nlm.nih.gov/pubmed/15681438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2375-2382.2005
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