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Epstein-Barr Virus Latent Membrane Protein-2A Induces ITAM/Syk- and Akt-Dependent Epithelial Migration through αV-Integrin Membrane Translocation

Epstein-Barr virus (EBV) is a highly prevalent herpesvirus associated with epithelial cancers, including nasopharyngeal carcinoma (NPC). The EBV protein latent membrane protein 2 (LMP2) is expressed in NPC tumor tissue and has been shown to induce transformation, inhibit differentiation, and promote...

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Detalhes bibliográficos
Main Authors: Fotheringham, Julie A., Coalson, Nicole E., Raab-Traub, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457296/
https://ncbi.nlm.nih.gov/pubmed/22837212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00853-12
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