Structure and characterization of a class 3B proline utilization A: Ligand-induced dimerization and importance of the C-terminal domain for catalysis

The bifunctional flavoenzyme proline utilization A (PutA) catalyzes the two-step oxidation of proline to glutamate using separate proline dehydrogenase (PRODH) and l-glutamate-γ-semialdehyde dehydrogenase active sites. Because PutAs catalyze sequential reactions, they are good systems for studying h...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Korasick, David A., Gamage, Thameesha T., Christgen, Shelbi, Stiers, Kyle M., Beamer, Lesa J., Henzl, Michael T., Becker, Donald F., Tanner, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465489/
https://ncbi.nlm.nih.gov/pubmed/28420730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786855
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