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A membrane-embedded pathway delivers general anesthetics to two interacting binding sites in the Gloeobacter violaceus ion channel

General anesthetics exert their effects on the central nervous system by acting on ion channels, most notably pentameric ligand-gated ion channels. Although numerous studies have focused on pentameric ligand-gated ion channels, the details of anesthetic binding and channel modulation are still debat...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Arcario, Mark J., Mayne, Christopher G., Tajkhorshid, Emad
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465477/
https://ncbi.nlm.nih.gov/pubmed/28420728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.780197
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