Adenovirus prime, Env protein boost vaccine protects against neutralization-resistant SIVsmE660 variants in rhesus monkeys

Previous studies have shown that DNA prime, Ad5 boost vaccines protect against neutralization-sensitive but not neutralization-resistant virus variants within the SIVsmE660 swarm. Here we show that Ad prime, Env protein boost vaccines protect against neutralization-resistant SIVsmE660 variants. We p...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Keele, Brandon F., Li, Wenjun, Borducchi, Erica N., Nkolola, Joseph P., Abbink, Peter, Chen, Bing, Seaman, Michael S., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465370/
https://ncbi.nlm.nih.gov/pubmed/28580942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15740
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