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Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay

Large-scale genetic studies are highly dependent on efficient and scalable multiplex SNP assays. In this study, we report the development of Molecular Inversion Probe technology with four-color, single array detection, applied to large-scale genotyping of up to 12,000 SNPs per reaction. While genera...

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Detalhes bibliográficos
Main Authors: Hardenbol, Paul, Yu, Fuli, Belmont, John, MacKenzie, Jennifer, Bruckner, Carsten, Brundage, Tiffany, Boudreau, Andrew, Chow, Steve, Eberle, Jim, Erbilgin, Ayca, Falkowski, Mat, Fitzgerald, Ron, Ghose, Sy, Iartchouk, Oleg, Jain, Maneesh, Karlin-Neumann, George, Lu, Xiuhua, Miao, Xin, Moore, Bridget, Moorhead, Martin, Namsaraev, Eugeni, Pasternak, Shiran, Prakash, Eunice, Tran, Karen, Wang, Zhiyong, Jones, Hywel B., Davis, Ronald W., Willis, Thomas D., Gibbs, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546528/
https://ncbi.nlm.nih.gov/pubmed/15687290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3185605
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