An Antigen-Presenting and Apoptosis-Inducing Polymer Microparticle Prolongs Alloskin Graft Survival by Selectively and Markedly Depleting Alloreactive CD8(+) T Cells

Selectively depleting the pathogenic T cells is a fundamental strategy for the treatment of allograft rejection and autoimmune disease since it retains the overall immune function of host. The concept of killer artificial antigen-presenting cells (KaAPCs) has been developed by co-coupling peptide–ma...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Wang, Wei, Shahzad, Khawar Ali, Li, Miaochen, Zhang, Aifeng, Zhang, Lei, Xu, Tao, Wan, Xin, Shen, Chuanlai
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465244/
https://ncbi.nlm.nih.gov/pubmed/28649247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00657
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