An Approach for a Synthetic CTL Vaccine Design against Zika Flavivirus Using Class I and Class II Epitopes Identified by Computer Modeling

The threat posed by severe congenital abnormalities related to Zika virus (ZKV) infection during pregnancy has turned development of a ZKV vaccine into an emergency. Recent work suggests that the cytotoxic T lymphocyte (CTL) response to infection is an important defense mechanism in response to ZKV....

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cunha-Neto, Edecio, Rosa, Daniela S., Harris, Paul E., Olson, Tim, Morrow, Alex, Ciotlos, Serban, Herst, Charles V., Rubsamen, Reid Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465239/
https://ncbi.nlm.nih.gov/pubmed/28649242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00640
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