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Oligomeric structure and chaperone-like activity of Drosophila melanogaster mitochondrial small heat shock protein Hsp22 and arginine mutants in the alpha-crystallin domain

The structure and chaperone function of DmHsp22WT, a small Hsp of Drosophila melanogaster localized within mitochondria were examined. Mutations of conserved arginine mutants within the alpha-crystallin domain (ACD) domain (R105G, R109G, and R110G) were introduced, and their effects on oligomerizati...

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Publicat a:Cell Stress Chaperones
Autors principals: Dabbaghizadeh, Afrooz, Finet, Stéphanie, Morrow, Genevieve, Moutaoufik, Mohamed Taha, Tanguay, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465034/
https://ncbi.nlm.nih.gov/pubmed/28389817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0784-y
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