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Oligomerization and chaperone-like activity of Drosophila melanogaster small heat shock protein DmHsp27 and three arginine mutants in the alpha-crystallin domain

The small Hsp DmHsp27 from Drosophila melanogaster is one of the few small heat shock proteins (sHsps) found within the nucleus. We report that its dimerization is independent of disulfide bond formation and seems to rely on salt bridges. Unlike metazoan sHsps, DmHsp27 forms two populations of oligo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Stress Chaperones
Hauptverfasser: Moutaoufik, Mohamed Taha, Morrow, Geneviève, Maaroufi, Halim, Férard, Céline, Finet, Stéphanie, Tanguay, Robert M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465024/
https://ncbi.nlm.nih.gov/pubmed/27933579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0748-7
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