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Rho GTPases: Anti- or Pro-neoplastic Targets?

Rho GTPases are critical signal transducers of multiple pathways. They have been proposed to be useful anti-neoplastic targets for over two decades, especially in Ras-driven cancers. Until recently, however, few in vivo studies had been carried out to test this premise. Several recent mouse model st...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Zandvakili, Inuk, Lin, Yuan, Morris, John C, Zheng, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464989/
https://ncbi.nlm.nih.gov/pubmed/27991930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.473
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