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DNA methylation profiling identifies the HOXA11 gene as an early diagnostic and prognostic molecular marker in human lung adenocarcinoma

DNA hypermethylation plays important roles in carcinogenesis by silencing key genes. The goal of our study was to identify pivotal genes using MethyLight and assessed their diagnostic and prognostic values in lung adenocarcinoma (AD). In the present study, we detected DNA methylation at sixteen loci...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Li, Qun, Chen, Chang, Ren, Xiaohui, Sun, Weihong
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464853/
https://ncbi.nlm.nih.gov/pubmed/28380439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16528
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