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DNA methylation profiling identifies the HOXA11 gene as an early diagnostic and prognostic molecular marker in human lung adenocarcinoma

DNA hypermethylation plays important roles in carcinogenesis by silencing key genes. The goal of our study was to identify pivotal genes using MethyLight and assessed their diagnostic and prognostic values in lung adenocarcinoma (AD). In the present study, we detected DNA methylation at sixteen loci...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Qun, Chen, Chang, Ren, Xiaohui, Sun, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464853/
https://ncbi.nlm.nih.gov/pubmed/28380439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16528
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