iNOS-derived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancer

Aerobic glycolysis is essential for tumor growth and survival. Activation of multiple carcinogenic signals contributes to metabolism reprogramming during malignant transformation of cancer. Recently nitric oxide has been noted to promote glycolysis but the mechanism remains elusive. We report here t...

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Pubblicato in:Oncotarget
Autori principali: Li, Linlin, Zhu, Lingqun, Hao, Bingtao, Gao, Wenwen, Wang, Qianli, Li, Keyi, Wang, Meng, Huang, Mengqiu, Liu, Zhengjun, Yang, Qiaohong, Li, Xiqing, Zhong, Zhuo, Huang, Wenhua, Xiao, Guanghui, Xu, Yang, Yao, Kaitai, Liu, Qiuzhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464849/
https://ncbi.nlm.nih.gov/pubmed/28380434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16523
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