iNOS-derived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancer

Aerobic glycolysis is essential for tumor growth and survival. Activation of multiple carcinogenic signals contributes to metabolism reprogramming during malignant transformation of cancer. Recently nitric oxide has been noted to promote glycolysis but the mechanism remains elusive. We report here t...

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Udgivet i:Oncotarget
Main Authors: Li, Linlin, Zhu, Lingqun, Hao, Bingtao, Gao, Wenwen, Wang, Qianli, Li, Keyi, Wang, Meng, Huang, Mengqiu, Liu, Zhengjun, Yang, Qiaohong, Li, Xiqing, Zhong, Zhuo, Huang, Wenhua, Xiao, Guanghui, Xu, Yang, Yao, Kaitai, Liu, Qiuzhen
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464849/
https://ncbi.nlm.nih.gov/pubmed/28380434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16523
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