Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma

Caspase-8 is a key player in extrinsic apoptosis and its activity is often downregulated in cancer. However, human Caspase-8 expression is retained in some tumors, including glioblastoma (GBM), suggesting that it may support cancer growth in these contexts. GBM, the most aggressive of the gliomas, i...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Fianco, Giulia, Mongiardi, Maria Patrizia, Levi, Andrea, De Luca, Teresa, Desideri, Marianna, Trisciuoglio, Daniela, Del Bufalo, Donatella, Cinà, Irene, Di Benedetto, Anna, Mottolese, Marcella, Gentile, Antonietta, Centonze, Diego, Ferrè, Fabrizio, Barilà, Daniela
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464770/
https://ncbi.nlm.nih.gov/pubmed/28594322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22593
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