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The enemy within: Targeting host–parasite interaction for antileishmanial drug discovery

The state of antileishmanial chemotherapy is strongly compromised by the emergence of drug-resistant Leishmania. The evolution of drug-resistant phenotypes has been linked to the parasites’ intrinsic genome instability, with frequent gene and chromosome amplifications causing fitness gains that are...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Lamotte, Suzanne, Späth, Gerald F., Rachidi, Najma, Prina, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464532/
https://ncbi.nlm.nih.gov/pubmed/28594938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005480
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