Analgesic and anti‐inflammatory properties of novel, selective, and potent EP4 receptor antagonists

Prostaglandin (PG) E(2) is the key driver of inflammation associated with arthritic conditions. Inhibitors of PGE (2) production (NSAIDs and Coxibs) are used to treat these conditions, but carry significant side effect risks due to the inhibition of all prostanoids that play important physiological...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Pharmacol Res Perspect
Päätekijät: Chandrasekhar, Srinivasan, Yu, Xiao‐Peng, Harvey, Anita K., Oskins, Jennifer L., Lin, Chaohua, Wang, Xushan, Blanco, Maria‐Jesus, Fisher, Matthew J., Kuklish, Steven L., Schiffler, Matthew A., Vetman, Tatiana, Warshawsky, Alan M., York, Jeremy S., Bendele, Alison M., Chambers, Mark G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464344/
https://ncbi.nlm.nih.gov/pubmed/28603634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.316
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