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SMO mutation status defines a distinct and frequent molecular subgroup in olfactory groove meningiomas

BACKGROUND. Meningiomas are the most common primary intracranial tumors in adults. Identification of SMO and AKT1 mutations in meningiomas has raised the hope for targeted therapies. It would be useful to know the precise frequency of these mutations in anatomical subgroups and clarify their prognos...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Boetto, Julien, Bielle, Franck, Sanson, Marc, Peyre, Matthieu, Kalamarides, Michel
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464306/
https://ncbi.nlm.nih.gov/pubmed/28082415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now276
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