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SMO mutation status defines a distinct and frequent molecular subgroup in olfactory groove meningiomas

BACKGROUND. Meningiomas are the most common primary intracranial tumors in adults. Identification of SMO and AKT1 mutations in meningiomas has raised the hope for targeted therapies. It would be useful to know the precise frequency of these mutations in anatomical subgroups and clarify their prognos...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Boetto, Julien, Bielle, Franck, Sanson, Marc, Peyre, Matthieu, Kalamarides, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464306/
https://ncbi.nlm.nih.gov/pubmed/28082415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now276
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