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P08.62 Extracellular signal-regulated kinase 1 (ERK1) mediates the autocrine positive feedback loop of TGF-β and furin in glioblastoma stem cells
Glioblastoma is the most common and aggressive intrinsic brain tumor in adults. Self-renewing, highly tumorigenic glioblastoma stem cells/glioma-initiating cells (GIC) have been linked to glioma invasive properties, immunomodulation and increased angiogenesis leading to resistance to therapy. TGF-β...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464254/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.251 |
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