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5′ CArG degeneracy in smooth muscle α-actin is required for injury-induced gene suppression in vivo
CC(A/T)(6)GG–dependent (CArG-dependent) and serum response factor–dependent (SRF-dependent) mechanisms are required for gene expression in smooth muscle cells (SMCs). However, an unusual feature of many SMC-selective promoter CArG elements is that they contain a conserved single G or C substitution...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546420/ https://ncbi.nlm.nih.gov/pubmed/15690088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522648 |
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