5′ CArG degeneracy in smooth muscle α-actin is required for injury-induced gene suppression in vivo

CC(A/T)(6)GG–dependent (CArG-dependent) and serum response factor–dependent (SRF-dependent) mechanisms are required for gene expression in smooth muscle cells (SMCs). However, an unusual feature of many SMC-selective promoter CArG elements is that they contain a conserved single G or C substitution...

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הוצא לאור ב:	J Clin Invest
Principais autores:	Hendrix, Jennifer A., Wamhoff, Brian R., McDonald, Oliver G., Sinha, Sanjay, Yoshida, Tadashi, Owens, Gary K.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Clinical Investigation 2005
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC546420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15690088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI22648
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