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P06.02 A multivalent protein for immune checkpoint inhibition at the tumor site

Monoclonal antibodies targeting programmed cell death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4, CTLA-4 on T cells have demonstrated efficacy in a variety of peripheral solid tumors. It is more challenging to exploit the potential of such a therapy in glioblastoma (GBM) patients becau...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Debinski, W., Rodriguez, A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464148/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.176
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