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P17.14 Connecting radiotherapy with targeted anti-glioma therapy using superparamagnetic nanoparticles conjugated with Granzyme B
Introduction: 70-kDa heat shock protein (Hsp70) is overexpressed on the membrane of the glioblastoma cells, but not on corresponding normal cells. Membrane-bound Hsp70 (i.e., mHsp70) is rapidly internalized into tumor cells and thus targeting the protein might provide a promising strategy for theran...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5463887/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.460 |
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