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P17.14 Connecting radiotherapy with targeted anti-glioma therapy using superparamagnetic nanoparticles conjugated with Granzyme B

Introduction: 70-kDa heat shock protein (Hsp70) is overexpressed on the membrane of the glioblastoma cells, but not on corresponding normal cells. Membrane-bound Hsp70 (i.e., mHsp70) is rapidly internalized into tumor cells and thus targeting the protein might provide a promising strategy for theran...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Shevtsov, M., Stangl, S., Sievert, W., Parr, M., Nikolaev, B., Illarionov, R., Marchenko, Y., Yakovleva, L., Ryzhov, V., Multhoff, G.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463887/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.460
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