Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813

BACKGROUND. The primary objective of this study was to compare the overall survival (OS) of patients with anaplastic astrocytoma (AA) treated with radiotherapy (RT) and either temozolomide (TMZ) or a nitrosourea (NU). Secondary endpoints were time to tumor progression (TTP), toxicity, and the effect...

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Опубликовано в: :Neuro Oncol
Главные авторы: Chang, Susan, Zhang, Peixin, Cairncross, J. Gregory, Gilbert, Mark R., Bahary, Jean-Paul, Dolinskas, Carol A., Chakravarti, Arnab, Aldape, Kenneth D., Bell, Erica H., Schiff, David, Jaeckle, Kurt, Brown, Paul D., Barger, Geoffrey R., Werner-Wasik, Maria, Shih, Helen, Brachman, David, Penas-Prado, Marta, Robins, H. Ian, Belanger, Karl, Schultz, Christopher, Hunter, Grant, Mehta, Minesh
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2017
Предметы:
Clinical Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463834/
https://ncbi.nlm.nih.gov/pubmed/27994066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now236
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