Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813

BACKGROUND. The primary objective of this study was to compare the overall survival (OS) of patients with anaplastic astrocytoma (AA) treated with radiotherapy (RT) and either temozolomide (TMZ) or a nitrosourea (NU). Secondary endpoints were time to tumor progression (TTP), toxicity, and the effect...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Chang, Susan, Zhang, Peixin, Cairncross, J. Gregory, Gilbert, Mark R., Bahary, Jean-Paul, Dolinskas, Carol A., Chakravarti, Arnab, Aldape, Kenneth D., Bell, Erica H., Schiff, David, Jaeckle, Kurt, Brown, Paul D., Barger, Geoffrey R., Werner-Wasik, Maria, Shih, Helen, Brachman, David, Penas-Prado, Marta, Robins, H. Ian, Belanger, Karl, Schultz, Christopher, Hunter, Grant, Mehta, Minesh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463834/
https://ncbi.nlm.nih.gov/pubmed/27994066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now236
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