P01.31 Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death

Glioblastomas (GBs) are characterized by a fast uncontrolled growth leading to hypoxic areas and necrosis. Signalling from epidermal growth factor receptor (EGFR) via mammalian target of rapamycin complex 1 (mTORC1) is one of the most commonly altered signalling pathways in GBs. Therefore, EGFR and...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Thiepold, A., Foltyn, M., Urban, H., Voss, M., Hofmann, U., Dröse, S., Harter, P. N., Mittelbronn, M., Steinbach, J. P., Ronellenfitsch, M. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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POSTER PRESENTATIONS
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463697/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.107
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