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P01.10 Dock4 heterozygous deletion normalizes the glioblastoma microenvironment & improves response to radiation

Introduction: Invasion and growth of brain tumours require cooperation of the tumour cell and endothelial cell compartments. Limited efficacy of anti-angiogenic therapy in glioblastoma is associated with activation of VEGF independent mechanisms, and the development of hypoxia. Those can be overcome...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Egnuni, T., Short, S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463696/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.086
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