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P01.10 METABOLIC CONDITIONS DETERMINE SENSITIVITY OF GLIOMA CELLS AGAINST EPIDERMAL-GROWTH FACTOR RECEPTOR (EGFR)-INHIBITION

The epidermal growth factor (EGFR) pathway is a frequently activated oncogenic pathway in glioblastoma. Nevertheless, the clinical results using EGFR inhibitors in glioma therapy are disappoiting. The reasons for the failure of these inhibitors are unclear but may involve factors of the tumor microe...

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Detalhes bibliográficos
Main Authors: Hartel, I.A., Wolking, S., Wanka, C., Ronellenfitsch, M.W., Steinbach, J.P., Rieger, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185443/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.103
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