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P01.33 Upregulated expression of the Aryl hydrocarbon receptor pathway in brain metastases from malignant melanoma
Objective: The Aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor initially linked to exogenic carcinogenic agents such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin). In 2011, the tryptophan (TRP) catabolite kynurenine (KYN) was identified as the first endogenous liga...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5463637/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.109 |
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