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CSIG-41. UPREGULATED EXPRESSION OF THE ARYL HYDROCARBON RECEPTOR PATHWAY IN BRAIN METASTASES FROM MALIGNANT MELANOMA
OBJECTIVE: The Aryl-hydrocarbon-receptor (AHR) is a ligand activated transcription factor linked to exogenic carcinogenic agents such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In 2011, the tryptophan (TRP) catabolite kynurenine (KYN) was identified as an endogenous ligand for AHR. The AHR is in...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693158/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.235 |
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