IL-6 inhibits upregulation of membrane-bound TGF-beta 1 on CD4+ T cells and blocking IL-6 enhances oral tolerance

Oral administration of antigen induces regulatory T cells that express latent membrane-bound TGF-beta (LAP) and that have been shown to play an important role in the induction of oral tolerance. We developed an in vitro model to study modulation of LAP+ on CD4+ T cells. The combination of anti-CD3 m...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Kuhn, Chantal, Rezende, Rafael Machado, M'Hamdi, Hanane, da Cunha, Andre Pires, Weiner, Howard L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463579/
https://ncbi.nlm.nih.gov/pubmed/28039301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600921
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items