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Effects of amiodarone on short QT syndrome variant 3 in human ventricles: a simulation study

BACKGROUND: Short QT syndrome (SQTS) is a newly identified clinical disorder associated with atrial and/or ventricular arrhythmias and increased risk of sudden cardiac death (SCD). The SQTS variant 3 is linked to D172N mutation to the KCNJ2 gene that causes a gain-of-function to the inward rectifier...

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Detalhes bibliográficos
Publicado no:Biomed Eng Online
Main Authors: Luo, Cunjin, Wang, Kuanquan, Zhang, Henggui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463381/
https://ncbi.nlm.nih.gov/pubmed/28592292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12938-017-0369-0
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