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DDX53 Regulates Cancer Stem Cell-Like Properties by Binding to SOX-2

This study investigated the role of cancer/testis antigen DDX53 in regulating cancer stem cell-like properties. DDX53 shows co-expression with CD133, a marker for cancer stem cells. DDX53 directly regulates the SOX-2 expression in anticancer drug-resistant Malme3M(R) cells. DDX53 and miR-200b were f...

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Bibliografski detalji
Izdano u:Mol Cells
Glavni autori: Kim, Youngmi, Yeon, Minjeong, Jeoung, Dooil
Format: Artigo
Jezik:Inglês
Izdano: Korean Society for Molecular and Cellular Biology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463040/
https://ncbi.nlm.nih.gov/pubmed/28535666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2017.0001
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