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Noncanonical cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1

Programmed cell death (PCD) occurs in several forms including apoptosis and necroptosis. Apoptosis is executed by the activation of caspases, while necroptosis is dependent on the receptor interacting protein kinase 3 (RIPK3). Precise control of cell death is crucial for tissue homeostasis. Indeed,...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Mihaly, September R., Sakamachi, Yosuke, Ninomiya-Tsuji, Jun, Morioka, Sho
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462742/
https://ncbi.nlm.nih.gov/pubmed/28592892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03112-1
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