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MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling

mTORC1 is the major homeostatic nutrient sensor for the cell. As such, it is integrated into diverse signaling networks and co-factor interactions that determine its activity. Our recent work implicates the mTORC1 co-factor and PI3K-related Kinase (PIKK) stabilizer, TELO2, in regulating mTORC1 activ...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Brown, Michael C., Gromeier, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462518/
https://ncbi.nlm.nih.gov/pubmed/28616583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1306010
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