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MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling

mTORC1 is the major homeostatic nutrient sensor for the cell. As such, it is integrated into diverse signaling networks and co-factor interactions that determine its activity. Our recent work implicates the mTORC1 co-factor and PI3K-related Kinase (PIKK) stabilizer, TELO2, in regulating mTORC1 activ...

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Podrobná bibliografie
Vydáno v:Mol Cell Oncol
Hlavní autoři: Brown, Michael C., Gromeier, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462518/
https://ncbi.nlm.nih.gov/pubmed/28616583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1306010
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