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Orthogonal modular gene repression in E. coli using engineered CRISPR/Cas9
The progress in development of synthetic gene circuits has been hindered by the limited repertoire of available transcription factors. Recently, it has been greatly expanded using the CRISPR/Cas9 system. However, this system is limited by its imperfect DNA sequence specificity, leading to potential...
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| Published in: | ACS Synth Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5462464/ https://ncbi.nlm.nih.gov/pubmed/26390083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.5b00147 |
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