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Efficacy of targeted drugs in germ cell cancer cell lines with differential cisplatin sensitivity

Testicular germ cell tumors (TGCTs) are the most common malignancies in men between the age of 15 and 35. Although cisplatin-based chemotherapy is highly effective in advanced disease, approximately 20% of patients have an unfavorable prognosis due to primary or acquired cisplatin resistance. For th...

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Опубликовано в: :PLoS One
Главные авторы: Schaffrath, Judith, Schmoll, Hans-Joachim, Voigt, Wieland, Müller, Lutz P., Müller-Tidow, Carsten, Mueller, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462387/
https://ncbi.nlm.nih.gov/pubmed/28591197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178930
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