Cellular basis for differential sensitivity to cisplatin in human germ cell tumour and colon carcinoma cell lines.

Cisplatin (CDDP) resistance mechanisms were studied in a model of three germ cell tumour and three colon carcinoma cell lines representing intrinsically CDDP-sensitive and -resistant tumours respectively. The CDDP sensitivity of the cell lines mimicked the clinical situation. The glutathione levels...

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Detalhes bibliográficos
Main Authors: Sark, M. W., Timmer-Bosscha, H., Meijer, C., Uges, D. R., Sluiter, W. J., Peters, W. H., Mulder, N. H., de Vries, E. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033748/
https://ncbi.nlm.nih.gov/pubmed/7710929
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