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NRP1 transport of cancer therapeutics mediated by tumor-penetrating peptides

Whereas uptake of low molecular weight agents is generally inhibited in tumors due to high interstitial pressure, tumor uptake of macromolecules is increased due to enhanced permeability and retention (EPR). Small molecule drugs alone or incorporated in nanoparticles (NP) have largely been dependent...

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Bibliografiske detaljer
Udgivet i:Drugs Future
Main Authors: Leng, Qixin, Woodle, Martin C, Mixson, A. James
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461880/
https://ncbi.nlm.nih.gov/pubmed/28603338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1358/dof.2017.042.02.2564106
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