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NRP1 transport of cancer therapeutics mediated by tumor-penetrating peptides

Whereas uptake of low molecular weight agents is generally inhibited in tumors due to high interstitial pressure, tumor uptake of macromolecules is increased due to enhanced permeability and retention (EPR). Small molecule drugs alone or incorporated in nanoparticles (NP) have largely been dependent...

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Détails bibliographiques
Publié dans:Drugs Future
Auteurs principaux: Leng, Qixin, Woodle, Martin C, Mixson, A. James
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461880/
https://ncbi.nlm.nih.gov/pubmed/28603338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1358/dof.2017.042.02.2564106
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