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KCNJ11, ABCC8 and TCF7L2 polymorphisms and the response to sulfonylurea treatment in patients with type 2 diabetes: a bioinformatics assessment

BACKGROUND: Type 2 diabetes (T2D) is a worldwide epidemic with considerable health and economic consequences. Sulfonylureas are widely used drugs for the treatment of patients with T2D. KCNJ11 and ABCC8 encode the K(ir)6.2 (pore-forming subunit) and SUR1 (regulatory subunit that binds to sulfonylure...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:BMC Med Genet
मुख्य लेखकों: Song, Jingwen, Yang, Yunzhong, Mauvais-Jarvis, Franck, Wang, Yu-Ping, Niu, Tianhua
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461698/
https://ncbi.nlm.nih.gov/pubmed/28587604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-017-0422-7
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