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Genome‐wide DNA methylation profiling of CpG islands in a morpholino anthracycline derivative‐resistant leukemia cell line: p38α as a novel candidate for resistance
Effective leukemia treatment is seriously hampered by drug resistance. We previously showed that aberrant methylation of the topoisomerase II α gene causes altered gene expression and acquired drug resistance in etoposide‐resistant leukemia cells. In this study, we analyzed the genome‐wide methylati...
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| Publicado no: | Pharmacol Res Perspect |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461645/ https://ncbi.nlm.nih.gov/pubmed/28596837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.285 |
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