Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

BACKGROUND: The APOE ε4 allele is the most significant common genetic risk factor for late-onset Alzheimer’s disease (LOAD). The region surrounding APOE on chromosome 19 has also shown consistent association with LOAD. However, no common variants in the region remain significant after adjusting for...

詳細記述

保存先:
書誌詳細
出版年:BMC Med Genomics
主要な著者: Nho, Kwangsik, Kim, Sungeun, Horgusluoglu, Emrin, Risacher, Shannon L., Shen, Li, Kim, Dokyoon, Lee, Seunggeun, Foroud, Tatiana, Shaw, Leslie M., Trojanowski, John Q., Aisen, Paul S., Petersen, Ronald C., Jack, Clifford R., Weiner, Michael W., Green, Robert C., Toga, Arthur W., Saykin, Andrew J.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2017
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461522/
https://ncbi.nlm.nih.gov/pubmed/28589856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-017-0267-0
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