Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer’s disease

BACKGROUND: Pathogenic mutations in PSEN1 are known to cause familial early-onset Alzheimer’s disease (EOAD) but common variants in PSEN1 have not been found to strongly influence late-onset AD (LOAD). The association of rare variants in PSEN1 with LOAD-related endophenotypes has received little att...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Nho, Kwangsik, Horgusluoglu, Emrin, Kim, Sungeun, Risacher, Shannon L., Kim, Dokyoon, Foroud, Tatiana, Aisen, Paul S., Petersen, Ronald C., Jack, Clifford R., Shaw, Leslie M., Trojanowski, John Q., Weiner, Michael W., Green, Robert C., Toga, Arthur W., Saykin, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989889/
https://ncbi.nlm.nih.gov/pubmed/27535542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-016-0190-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados