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Differential activation of DNA-PK based on DNA strand orientation and sequence bias
DNA-PKcs and Ku are essential components of the complex that catalyzes non-homologous end joining (NHEJ) of DNA double-strand breaks (DSBs). Ku, a heterodimeric protein, binds to DNA ends and facilitates recruitment of the catalytic subunit, DNA-PKcs. We have investigated the effect of DNA strand or...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC546145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15640450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gki157 |
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