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Differential activation of DNA-PK based on DNA strand orientation and sequence bias
DNA-PKcs and Ku are essential components of the complex that catalyzes non-homologous end joining (NHEJ) of DNA double-strand breaks (DSBs). Ku, a heterodimeric protein, binds to DNA ends and facilitates recruitment of the catalytic subunit, DNA-PKcs. We have investigated the effect of DNA strand or...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546145/ https://ncbi.nlm.nih.gov/pubmed/15640450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki157 |
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